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Structure Elucidation Expert with Focus on Mass Spectrometry(m/w/x)
Analyzing unknown impurities in lab experiments using LC-HRMS, 2D-LC-HRMS, and GC-HRMS. 5 years hands-on structure elucidation with LC-HRMS and in-depth HRMS/MS spectra interpretation for small molecules, peptides, or oligonucleotides required. Collaborative work guiding project teams in a global pharmaceutical setting.
Anforderungen
- Higher education (Master's or PhD in Chemistry, Biochemistry, or related field) or apprenticeship as a laboratory technician
- Minimum of 5 years of direct, hands-on experience in structure elucidation using LC-HRMS
- Proven, in-depth experience in interpreting high-resolution MS and MS/MS spectra for small molecules, peptides, or oligonucleotides
- Hands-on skills in developing and optimizing chromatographic (HPLC, GC) and mass spectrometry methods
- Basic NMR experience
- Pragmatic, proactive, solution-oriented, and accurate workstyle
- Excellent communication skills and fluency in English and proficiency in German
- Keen interest in digital innovation with exposure to tools like GeneData Expressionist®, ACD/Labs or programming languages (Python, JavaScript)
- Practical experience with maintenance and troubleshooting of HPLC, GC and MS instrumentation
- Comfortable and experienced in working with MS instruments and software from various vendors
Aufgaben
- Design and execute lab experiments for structure elucidation
- Analyze unknown impurities from process development and degradation studies
- Utilize qualitative LC-HRMS, 2D-LC-HRMS, and GC-HRMS techniques
- Evaluate and interpret complex analytical data
- Provide clear conclusions to guide project teams
- Support regulatory filings with analytical insights
- Identify opportunities to enhance workflows
- Evaluate new software tools for analytical improvement
- Collaborate with project leads and stakeholders
- Communicate analytical insights for project integration
- Participate in cross-functional projects
- Share knowledge and insights with colleagues
Berufserfahrung
- 5 Jahre
Ausbildung
- Abgeschlossene Berufsausbildung
Sprachen
- Englisch – verhandlungssicher
- Deutsch – Grundkenntnisse
Tools & Technologien
- LC-HRMS
- HPLC
- GC
- MS
- NMR
- GeneData Expressionist®
- ACD/Labs
- Python
- JavaScript
Noch nicht perfekt?
- 1201 F. Hoffmann-La Roche AGVollzeitnur vor OrtBerufserfahrenBasel
- Roche
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Structure Elucidation Expert with Focus on Mass Spectrometry(m/w/x)
Analyzing unknown impurities in lab experiments using LC-HRMS, 2D-LC-HRMS, and GC-HRMS. 5 years hands-on structure elucidation with LC-HRMS and in-depth HRMS/MS spectra interpretation for small molecules, peptides, or oligonucleotides required. Collaborative work guiding project teams in a global pharmaceutical setting.
Anforderungen
- Higher education (Master's or PhD in Chemistry, Biochemistry, or related field) or apprenticeship as a laboratory technician
- Minimum of 5 years of direct, hands-on experience in structure elucidation using LC-HRMS
- Proven, in-depth experience in interpreting high-resolution MS and MS/MS spectra for small molecules, peptides, or oligonucleotides
- Hands-on skills in developing and optimizing chromatographic (HPLC, GC) and mass spectrometry methods
- Basic NMR experience
- Pragmatic, proactive, solution-oriented, and accurate workstyle
- Excellent communication skills and fluency in English and proficiency in German
- Keen interest in digital innovation with exposure to tools like GeneData Expressionist®, ACD/Labs or programming languages (Python, JavaScript)
- Practical experience with maintenance and troubleshooting of HPLC, GC and MS instrumentation
- Comfortable and experienced in working with MS instruments and software from various vendors
Aufgaben
- Design and execute lab experiments for structure elucidation
- Analyze unknown impurities from process development and degradation studies
- Utilize qualitative LC-HRMS, 2D-LC-HRMS, and GC-HRMS techniques
- Evaluate and interpret complex analytical data
- Provide clear conclusions to guide project teams
- Support regulatory filings with analytical insights
- Identify opportunities to enhance workflows
- Evaluate new software tools for analytical improvement
- Collaborate with project leads and stakeholders
- Communicate analytical insights for project integration
- Participate in cross-functional projects
- Share knowledge and insights with colleagues
Berufserfahrung
- 5 Jahre
Ausbildung
- Abgeschlossene Berufsausbildung
Sprachen
- Englisch – verhandlungssicher
- Deutsch – Grundkenntnisse
Tools & Technologien
- LC-HRMS
- HPLC
- GC
- MS
- NMR
- GeneData Expressionist®
- ACD/Labs
- Python
- JavaScript
Über das Unternehmen
1201 F. Hoffmann-La Roche AG
Branche
Healthcare
Beschreibung
Roche is dedicated to advancing science and ensuring access to healthcare for everyone, with over 100,000 employees globally.
Noch nicht perfekt?
- 1201 F. Hoffmann-La Roche AG
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Senior Expert Science & Technology (Analytical Chemistry Oligonucleotides)(m/w/x)
Vollzeitnur vor OrtSeniorBasel - dsm-firmenich
PostDoc Analytical Sciences(m/w/x)
Vollzeitnur vor OrtBerufserfahrenKaiseraugst - Novartis Pharma AG
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