Beschreibung

As a Toxicology Lead, you will play a pivotal role in shaping safety assessment strategies for drug discovery, collaborating with AI and ML teams to enhance predictive models while mentoring junior scientists and fostering an inclusive culture.

Anforderungen

• •Ph.D. in Toxicology, Pharmacology, Biology, or DVM/MD with relevant experience
• •Board Certification
• •7–10+ years' professional experience in a Toxicology role
• •Demonstrated experience filing successful INDs/CTAs for small molecules and biologics
• •Deep understanding of Global Regulatory Guidelines regarding safety assessment
• •Experience partnering closely with Discovery and Clinical teams
• •Excellent communication and interpersonal skills
• •Creative problem solving with a strong growth mindset
• •Experience with peptides and other new modalities
• •Good understanding of machine learning techniques
• •Familiarity with Python and KNIME

Aufgaben

• •Design and implement safety assessment strategies for drug discovery projects
• •Create screening cascades and mechanistic experiments to support project progression
• •Develop structure-activity relationship (SAR) understanding of toxicology liabilities
• •Define regulatory safety assessment packages for agency acceptance
• •Author toxicology sections of regulatory documents
• •Collaborate with Machine Learning colleagues to enhance predictive toxicology models
• •Identify and evaluate state-of-the-art technologies for platform improvement
• •Maintain relationships with CROs to ensure timely data generation
• •Leverage external scientific expertise to enhance team impact
• •Oversee data generation campaigns for AI-based toxicology models
• •Mentor junior team members
• •Promote a culture of inclusion and continuous professional development

Tools & Technologien