Roche
Post Doctorate Scientist (IHB) - In Vitro Modeling Adaptive Immunologist(m/w/x)
Vollzeitnur vor OrtBerufserfahren
Basel
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F.F. Hoffmann-La Roche AG
Post Doctoral Scientist (IHB) - Computational Immunology(m/w/x)
Basel
VollzeitVor OrtBerufserfahren
Data Science
Nejo KI-Zusammenfassung
Computational research on immune cell states in human neuroinflammation, integrating multi-omic datasets. Ph.D. in related field, completed within last four years, required. Early-career focus, R/Python programming, single-cell/spatial data experience.
Anforderungen
- Ph.D. in Immunology, Computational Biology, Bioinformatics, Systems Biology, or related field
- Early-career researcher, Ph.D. completed within last four years
- Strong programming skills in R and Python
- Experience with multi-omic datasets, ideally single-cell and/or spatial
- Expertise in T- and B-cell biology analysis
- Knowledge of immune cell subsets and heterogeneity
- Experience with immune repertoire profiling (AIRR-seq, Rep-seq, scRNA-seq + VDJ)
- Experience with shared computing clusters / HPC environments
- Strong interest in human immunology and neuroinflammation
- Ability to work effectively across scientific functions
- Ability to build strong, productive collaborations
- Strong communication skills
- Professional fluency in spoken and written English
- Proactive, “go-getter” mindset
- Ability to manage priorities
- Ability to adapt as research evolves
- Contribute to a team-oriented culture
- Research experience in adaptive neuroinflammation
- Knowledge of meningeal biology
- Knowledge of tissue-specific immune niches
- Experience analyzing spatial transcriptomics, proteomics, or related spatial omics
- Familiarity with stromal biology
- Experience with human translational and multi-omic datasets
- Experience as an experimental scientist
- Experience in close partnership with wet-lab teams
- Strong understanding of experimental design
- Strong understanding of technical execution of assays
- Strong understanding of assay limitations
- Interest in translating human biology insights into therapeutic strategies
Aufgaben
- Lead computational research on immune cell states in human neuroinflammation
- Integrate multi-omic datasets to uncover disease mechanisms and therapeutic targets
- Contribute to developing a comprehensive human atlas of neuroinflammation
- Identify cellular states and molecular signatures in healthy and diseased donors
- Apply computational and biological insights to high-dimensional datasets
- Generate hypotheses and guide future translational research
- Analyze T- and B-cell repertoires using high-throughput methods
- Conduct AIRR-seq, Rep-seq, and scRNA-seq + VDJ dataset analyses
- Collaborate with IHB and pRED scientists across various fields
- Translate human biology findings into portfolio-relevant questions and strategies
- Contribute to scientific manuscripts, internal presentations, and conference talks
- Communicate computational and biological findings to diverse audiences
- Support a collaborative and inclusive research culture
Berufserfahrung
- ca. 1 - 4 Jahre
Ausbildung
- Doktor / Ph.D.
Sprachen
- Englisch – verhandlungssicher
Tools & Technologien
- R
- Python
- AIRR-seq
- Rep-seq
- scRNA-seq
- VDJ
Die Originalanzeige dieses Stellenangebotes in der aktuellsten Version findest du hier. Nejo hat diesen Job automatisch von der Website des Unternehmens F. Hoffmann-La Roche AG erfasst und die Informationen auf Nejo mit Hilfe von KI für dich aufbereitet. Trotz sorgfältiger Analyse können einzelne Informationen unvollständig oder ungenau sein. Bitte prüfe immer alle Angaben in der Originalanzeige! Inhalte und Urheberrechte der Originalanzeige liegen beim ausschreibenden Unternehmen.
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F.F. Hoffmann-La Roche AG
Post Doctoral Scientist (IHB) - Computational Immunology(m/w/x)
Basel
VollzeitVor OrtBerufserfahren
Data Science
Nejo KI-Zusammenfassung
Computational research on immune cell states in human neuroinflammation, integrating multi-omic datasets. Ph.D. in related field, completed within last four years, required. Early-career focus, R/Python programming, single-cell/spatial data experience.
Anforderungen
- Ph.D. in Immunology, Computational Biology, Bioinformatics, Systems Biology, or related field
- Early-career researcher, Ph.D. completed within last four years
- Strong programming skills in R and Python
- Experience with multi-omic datasets, ideally single-cell and/or spatial
- Expertise in T- and B-cell biology analysis
- Knowledge of immune cell subsets and heterogeneity
- Experience with immune repertoire profiling (AIRR-seq, Rep-seq, scRNA-seq + VDJ)
- Experience with shared computing clusters / HPC environments
- Strong interest in human immunology and neuroinflammation
- Ability to work effectively across scientific functions
- Ability to build strong, productive collaborations
- Strong communication skills
- Professional fluency in spoken and written English
- Proactive, “go-getter” mindset
- Ability to manage priorities
- Ability to adapt as research evolves
- Contribute to a team-oriented culture
- Research experience in adaptive neuroinflammation
- Knowledge of meningeal biology
- Knowledge of tissue-specific immune niches
- Experience analyzing spatial transcriptomics, proteomics, or related spatial omics
- Familiarity with stromal biology
- Experience with human translational and multi-omic datasets
- Experience as an experimental scientist
- Experience in close partnership with wet-lab teams
- Strong understanding of experimental design
- Strong understanding of technical execution of assays
- Strong understanding of assay limitations
- Interest in translating human biology insights into therapeutic strategies
Aufgaben
- Lead computational research on immune cell states in human neuroinflammation
- Integrate multi-omic datasets to uncover disease mechanisms and therapeutic targets
- Contribute to developing a comprehensive human atlas of neuroinflammation
- Identify cellular states and molecular signatures in healthy and diseased donors
- Apply computational and biological insights to high-dimensional datasets
- Generate hypotheses and guide future translational research
- Analyze T- and B-cell repertoires using high-throughput methods
- Conduct AIRR-seq, Rep-seq, and scRNA-seq + VDJ dataset analyses
- Collaborate with IHB and pRED scientists across various fields
- Translate human biology findings into portfolio-relevant questions and strategies
- Contribute to scientific manuscripts, internal presentations, and conference talks
- Communicate computational and biological findings to diverse audiences
- Support a collaborative and inclusive research culture
Berufserfahrung
- ca. 1 - 4 Jahre
Ausbildung
- Doktor / Ph.D.
Sprachen
- Englisch – verhandlungssicher
Tools & Technologien
- R
- Python
- AIRR-seq
- Rep-seq
- scRNA-seq
- VDJ
Die Originalanzeige dieses Stellenangebotes in der aktuellsten Version findest du hier. Nejo hat diesen Job automatisch von der Website des Unternehmens F. Hoffmann-La Roche AG erfasst und die Informationen auf Nejo mit Hilfe von KI für dich aufbereitet. Trotz sorgfältiger Analyse können einzelne Informationen unvollständig oder ungenau sein. Bitte prüfe immer alle Angaben in der Originalanzeige! Inhalte und Urheberrechte der Originalanzeige liegen beim ausschreibenden Unternehmen.
Über das Unternehmen
F. Hoffmann-La Roche AG
Branche
Pharmaceuticals
Beschreibung
Das Unternehmen ist ein führender Anbieter von pharmazeutischen Wirkstoffen und setzt sich für die Gesundheitsversorgung weltweit ein.
Noch nicht perfekt?
- Roche
Post Doctorate Scientist (IHB) - In Vitro Modeling Adaptive Immunologist(m/w/x)
Vollzeitnur vor OrtBerufserfahrenBasel - F. Hoffmann-La Roche AG
Post Doctorate Scientist - Single Cell Technologies(m/w/x)
Vollzeitnur vor OrtSeniorBasel - Roche
Sr. Scientist - Computational Biology(m/w/x)
Vollzeitnur vor OrtBerufserfahrenBasel - 1201 F. Hoffmann-La Roche AG
Post Doctorate Scientist Single Cell Technologies(m/w/x)
Vollzeitnur vor OrtBerufserfahrenBasel - F. Hoffmann-La Roche AG
PhD Student in Single Cell Technologies(m/w/x)
Vollzeitnur vor OrtSeniorBasel